Endothelial cell proliferation is dependent on Nox4‐containing NADPH oxidases whereas Nox2 is anti‐apoptotic
نویسندگان
چکیده
منابع مشابه
NADPH oxidase Nox2 is required for hypoxia-induced mobilization of endothelial progenitor cells.
RATIONALE Endothelial progenitor cells (EPCs, defined as sca-1(+)flk-1(+)lin(-) mononuclear blood cells) contribute to vascular repair. The role of hypoxia and reactive oxygen species (ROS) in mobilization and function of these cells is incompletely understood. OBJECTIVE We studied the contribution of the NADPH oxidase Nox2, an important vascular source of ROS in this context. METHODS AND R...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2008
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.22.1_supplement.964.18